产品货号：
GS4708
中文名称：
重组大鼠IL-9
英文名称：
Recombinant Rat Interleukin-9
产品规格：
2μg
发货周期：
1～3天
产品价格：
询价
分子量：Approximately 14.3kDa,a single non-glycosylated polypeptide chain containing 127 amino acids.
储存条件：冷冻（-20℃）
概述
Interleukin-9(IL-9)is encoded by the IL9 gene and produced by T-cells and specifically by CD4+ helper cells.IL-9 was originally identified as a cytokine found in the conditioned medium of a human T cell leukemia virus type I(HTLVI)transformed T cell line.It functions through the IL-9 receptor,which activates different signal transducer and activator(STAT)proteins and thus connects this cytokine to various biological processes.IL-9 can support the growth of IL-2 independent and IL-4 independent helper T-cells.Rat IL-9 has approximately 73%amino acid sequence identity with murine IL-9.The gene encoding this cytokine has been identified as a candidate gene for asthma.Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
相关搜索：重组大鼠IL-9，IL-9, Rat，Recombinant Rat Interleukin-9
储存条件：冷冻（-20℃）
概述
Interleukin-9(IL-9)is encoded by the IL9 gene and produced by T-cells and specifically by CD4+ helper cells.IL-9 was originally identified as a cytokine found in the conditioned medium of a human T cell leukemia virus type I(HTLVI)transformed T cell line.It functions through the IL-9 receptor,which activates different signal transducer and activator(STAT)proteins and thus connects this cytokine to various biological processes.IL-9 can support the growth of IL-2 independent and IL-4 independent helper T-cells.Rat IL-9 has approximately 73%amino acid sequence identity with murine IL-9.The gene encoding this cytokine has been identified as a candidate gene for asthma.Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
| 外观 | Sterile Filtered White lyophilized(freeze-dried)powder. |
| 纯度 | ＞97%by SDS-PAGE and HPLC analyses. |
| 来源 | Escherichia coli. |
| 生物活性 | Fully biologically active when compared to standard.The ED50 as determined by a cell proliferation assay using murine TS1 cells is less than 10ng/ml,corresponding to a specific activity of>1.0×105 IU/mg. |
| 成分 | Lyophilized from a 0.2μmfiltered concentrated solution in PBS,pH 7.4. |
| 内毒素 | Less than 0.1 EU/μg of rRtIL-9 as determined by LAL method. |
| 复溶 | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions. |
| 氨基酸序列 | MQRCSTSWGI QHTSYLIENL KDDPSSKCSC SANVTSCLCL PIPSDDCTTP CFQEGMSQVT NATQQSKFSP FFFRVKRIVE TLKSNKCQFF SCEKPCNQTT AGNTVSFLKS LLKTFQKTEV QVQRSRA |
相关搜索：重组大鼠IL-9，IL-9, Rat，Recombinant Rat Interleukin-9